Abin da Kuna Bukatar Ku sani kuma Ku Tsare Idan kun kasance a kan Theophylline
Theophylline ne mai methylxanthine wanda shine magunguna ne kuma yana iya kasancewa mai tasirin maganin ƙwayar cutar. Yayin da za'a iya amfani da shi azaman mai gyara, magani mai mahimmanci tare da steroid wanda aka yi amfani da shi , wannan ba likitanci ne wanda aka fi so idan ci gaba da ƙwayar ƙwayar buƙata ta buƙaci ƙarin magani don kula da fuka. Theophylline ya zama mafi shahararrun lokaci sannan kuma ya zama mummunan ni'ima tare da likitoci masu kula da asma.
Duk da haka, daya daga cikin abubuwan da ya fi amfani da ita idan aka kwatanta da duk sauran jiyya na ƙwayar asiri shi ne cewa ba shi da tsada. Wannan ya sa ya fi dacewa a matsayin magani mai maimaitawa a bayan magungunan ƙwayar sanyi wanda ba shi da isasshen ƙwayar cuta ba zai iya kula da maganin fuka-fuka ba a zukatan marasa lafiya.
Saboda hoton na iya wucewa har zuwa sa'o'i 24, wasu likitoci za su yi amfani da toophylline don samun iko da bayyanar cututtuka na yau da kullum, musamman ga maƙarƙashiya mai tsauri ko matsakaici .
Ta yaya Theophylline ke aiki
Theophylline wani magani ne mai kula da aiki wanda yake aiki a matsayin magungunan ƙwayar cuta kuma ya danganta da tsokoki da suka ƙarfafa a matsayin ɓangare na fuka. Theophylline kuma yana da ƙwayoyin magungunan ƙwayoyin cuta da kuma abubuwan da ke da magungunan bronchoprotective wanda zai yiwu ya bayyana yadda yake da ikon taimakawa wajen bayyanar cututtukan fuka da ƙwayoyi fiye da magungunan bronchodilatory kawai.
Saboda wasu hanyoyin da suka fi dacewa kamar su steroids (wadanda likitoci a horo a yau basu da kwarewa sosai tare da miyagun ƙwayoyi kamar yadda muka kasance a cikin lokacin da ya ƙare tare da al'umman kiwon lafiya), masu aikin beta agamai (LABAs) da leukotriene masu gyara, toophylline ba a umarce su ba ne a matsayin likita na farko ko na biyu don maganin fuka da likitan ku.
Dalili dalili shine asophylline ya fadi daga ni'ima shine ba zaiyi aiki da sauran magunguna ba. Nazarin binciken ba a nuna cewa theophylline daidai yake da steroid din inhaled a maganin fuka. Hakazalika, nazarin ya nuna cewa LABA sun fi tasiri yayin da suka hada da miyagun ƙwayoyi na biyu a kan ƙara theophylline.
Theophylline yana buƙatar wasu matakan jini don a cimma su don samun sakamako mai illa amma har ma zai iya haifar da sakamako mai tasiri idan matakin ya wuce. Doctors sukan kwatanta wannan a matsayin iyakokin maganin warkewa.
Theophylline yana kasuwa a ƙarƙashin sunayen sunaye:
- Elixophyllin
- Theo-24
- Theo-Bid Duracap
- TheoCap
- Theochron
- Theo-Dur
- Theo-Dur Sprinkle
- Theolair
- Theovent LA
- Slo Bid
- Slo-Phyllin
- Uniphyl
Kulawa na Theophylline
Bugu da ƙari ga illa mai lalacewa, marasa lafiya guda daya ba sa son yin amfani da toophylline shi ne cewa za a buƙaci ka zubar da jini don saka idanu a cikin jinin kaophylline. Dangane da yadda kake yin aiki, zaka iya buƙatar yin haka kamar yadda sau ɗaya a wata har sai ka cimma daidaituwa, tasirin ilimin theophylline a jininka. Kullum, likitan ku na ƙoƙarin samun matakin toophylline cikin jini na 5-15 μg / ml. Idan matakin kaophylline ya kasance a sama da wannan matakin, kana da damar da za ka iya samun sakamako mai tasiri.
Bugu da ƙari, yana da muhimmanci a bari duk likitan da kake gani san cewa kana kan laophylline. Saboda theophylline yana hulɗar da kwayoyi daban-daban, kowane likita da kake gani yana bukatar ya san kai kan kanophylline ne. Nazarin ya nuna kusan kashi 35 cikin dari na marasa lafiya a kan toophylline an tsara wasu maganin da suke hulɗa da theophylline.
Wasu magunguna da ke hulɗa da theophylline sun hada da:
- Allopurinol: Zai iya ƙara yawan jini na theophylline
- Benzodiazepines: Theophylline na iya rage sakamako
- Beta-Blockers : Zai iya rage sakamako na bronchodilatation na toophylline
- Carbamazepine: Theophylline na iya rage matakan jini kuma ƙara haɗarin haɗari
- Ciprofloxacin: Matakan toophylline sun karu da wannan kwayoyin cutar da sauran maganin rigakafi a wannan aji. Idan ka karɓi IVopophylline da IV ciprofloxacin ta hanyar jinsin IV, za'a iya yin cristallization
- Formoterol: Theophylline yana ƙara haɗarin rashin potassium
- Zafirlukast: Theophylline na iya rage yawan jini na zafirlukast
- Zileuton: Zai iya ƙara yawan jima'i na toophylline
Har ila yau, idan kana da wasu matsalolin likita ko yanayi kana bukatar ka yi hankali idan ka dauki theophylline:
- Tashin cutar: Idan kana da matsalolin hanta jikinka ba zai haifar da toophylline ba a matsayin mutum na al'ada, kuma ana bukatar raguwar kashi naka.
- Cushewar zuciya mai rikitarwa: Dole ne a rage ƙyama kamar yadda cutar ta hanta
- Shan taba: Idan kina shan taba, zaka iya buƙatar kashi mafi girma na theophylline. Har ila yau, idan ka yanke shawarar dakatar da shan taba za ka iya buƙatar rage yawan kashi na kaophylline.
Sha'idodi na yanzu don Theophylline
Akwai yankunan da dama da ake amfani da su a matsayin mai amfani da asophylline a yau a maganin fuka:
- A matsayin matakan gyaran kafa lokacin da inhaled steroids ba su kula da bayyanar cututtukan fuka ko kuma lokacin da aka kara wasu wakilai ( LABAs) ko ( leukotriene masu gyare-gyare) kuma basu da tasiri wajen sarrafa sifofin.
- A matsayin magunguna na farko idan mai haƙuri ba ya bi (ko kuma yana da wuya ko tsauraran) zuwa steroid da aka yiwa inhaled kuma wani canji na leukotriene ba zai tasiri ba.
- Lokacin da mai haƙuri ya kasance a cikin kulawa mai kulawa mai tsanani tare da tsananin mummunar ƙwayar asiri kuma ba amsa ga sauran jiyya ba.
Theophylline Side Effects
Ɗaya daga cikin dalilan da ya sa dalilai ba a amfani dashi ba ne saboda sakamako masu illa. Mutane da yawa marasa lafiya, duk da haka, ba su da wani sakamako mai illa a kan theophylline. Wasu marasa lafiya suna shawo kan illa a cikin makon farko na magani tare da theophylline. Idan zaka iya jurewa da farko, jikinka zai iya zama mai haƙuri. Kwayar cututtuka da za a yi amfani da jikinka, amma kana bukatar ka yi magana da likitanka idan ba su tafi ba, sun hada da:
- Raunin rashin tausayi ko zafi
- Diarrhea
- Ciwon kai
- Insomnia
- Madaba
- Ƙaruwa
Ƙarin sakamako mai tsanani da ke buƙatar sanar da likitanku da sauri ya haɗa da:
- Zuciya marar ciki yana damuwa ko rashin
- Riƙe
- Cikakken fata
- Vomiting
Sources:
Pashko S, Simons WR, Sena MM, Stoddard ML. Adadin yawan abin da ke nunawa ga hulɗar magungunan zane-zane na toophylline. Clin Ther. 1994 Nov-Dec, 16 (6): 1068-77.
> UpToDate. Theophylline: Bayanin maganin miyagun ƙwayoyi
Cibiyar Zuciya ta Duniya, Lung, da Ciwon jini. Rukunin Sakamakon Kwararri na 3 (EPR3): Sharuɗɗa don Bincike da Gudanarwa na Tsira